SYSTEMS BIOLOGY OF AGING

Editorial: Biology of Cognitive Aging: Model Systems, Technologies, and Beyond

Age-related memory impairment (AMI), also called age-associated memory impairment (AAMI), describes the normal emergence and progression of memory problems associated with aging. It is one of diverse age-associated phenotypes found across a variety of organisms, including bees, fruit flies, nematodes, snails, rodents, and humans. The goal of this editorial is to provide an overview of our curre...

Biology of Aging

Molecular Biology of Aging

of premature aging in affected people; physiological exIntroduction periments that relate the pace of aging to caloric intake; Is aging the final act in the script of developmental bioland advances in human genetics, as well as cell and ogy? The characteristic changes that are part and parcel molecular biology leading to an understanding of the of aging appear similar to developmentally regulat...

Biology of Aging

In spite of the substantial success of modern medicine in curing specific diseases and greatly increasing the average life-span, there has been a complete failure to alter the maximum age that human beings can attain. We live no longer than our ancestors. Marion Lamb's excellent book is devoted to the apparently irreversible process of senescence, and represents a considerable achievement in re...

Molecular biology of aging.

Aging seems to reflect a patterned program of decline in functional reserves and a reduced ability to maintain homeostasis. Advances in molecular biology have provided new insights into the process of aging at the cellular level. In this review, a few selected models of aging that illustrate the molecular methods and techniques used in aging research are discussed.